All research and publications are written and done by residents with supervision of attendings.
Research Rotation is a 2-week rotation given to interested residents under the supervision of our Research Director, Dr. Vidya Menon to work on starting a project that they have in mind. The hospital has its own (Internal Review Board) IRB. The program has 5 assigned Research Assistants to assist in all our research related activities.
Every year, the entire hospital has a Research Competition participated by different departments showcasing all research products related to their own specific department.
The Department supports residents in presentation of their works into various societies and conferences.
The following are few of what the program has made last year:
- COVID-Related Publications
- 1) SARS-CoV-2 Seroprevalence Among Health Care Workers in a New York City Hospital: A Cross-Sectional Analysis During the COVID-19 Pandemic Int J Infect Dis. 2021; 102:63-69. doi:10.1016/j.ijid.2020.10.036
2) Prone Positioning in Moderate to Severe Acute Respiratory Distress Syndrome due to COVID-19: A Cohort Study and Analysis of Physiology- J Intensive Care Med. 2021 Feb;36(2):241-252. doi: 10.1177/0885066620980399. PMID: 33380236; PMCID: PMC7780273.
3) Does HIV infection influence clinical course of Covid-19? Risk factors and outcomes in Covid-19 patients with and without HIV coinfection in New York City: an observational cohort study- Undergoing Peer Review in JID
4) Impact of Residential Neighborhood and Race/Ethnicity on Outcomes of Hospitalized Patients with COVID-19 in the Bronx- medRxiv preprint doi:https://doi.org/10.1101/2021.01.09.21249515;
5) Empiric use of anticoagulation in hospitalized patients with COVID-19: a propensity score-matched study of risks and benefits- Undergoing Peer Review in Experimental Hematology and Oncology
6) Comparison of clinical course and outcomes of critically ill patients with SARS-CoV2 infection managed in traditional ICU and ‘Flex’ ICU during the surge of the pandemic- Undergoing Peer Review
- https://pubmed.ncbi.nlm.nih.gov/33075539/
- https://pubmed.ncbi.nlm.nih.gov/32802620/
- https://pubmed.ncbi.nlm.nih.gov/32670730/
- https://pubmed.ncbi.nlm.nih.gov/32775110/
- https://pubmed.ncbi.nlm.nih.gov/31187012/
- https://pubmed.ncbi.nlm.nih.gov/31453078/
- https://pubmed.ncbi.nlm.nih.gov/32951878/
- https://pubmed.ncbi.nlm.nih.gov/32946431/
- https://pubmed.ncbi.nlm.nih.gov/30937283/
- https://pubmed.ncbi.nlm.nih.gov/30891324/
- https://pubmed.ncbi.nlm.nih.gov/32963855/
- https://pubmed.ncbi.nlm.nih.gov/31293892/
- https://pubmed.ncbi.nlm.nih.gov/32775110/
- https://pubmed.ncbi.nlm.nih.gov/31762567/
- https://pubmed.ncbi.nlm.nih.gov/31762865/
- https://pubmed.ncbi.nlm.nih.gov/32802620/
- https://pubmed.ncbi.nlm.nih.gov/33564511/
- https://pubmed.ncbi.nlm.nih.gov/32864275/
- https://pubmed.ncbi.nlm.nih.gov/32802626/
Current Funded Trials:
Ongoing Pharmaceutical: COVID-19
1. Regeneron 2066- A Master protocol assessing the safety, tolerability, and efficacy of anti-spike (S) SARS-CoV2 monoclonal antibodies for thetreatment of hospitalized patients with COVID-19
2. Regeneron 2067- A master protocol for assessing the safety, tolerability, and efficacy of anti-Spike (S) SARS-CoV2 monoclonal antibodies for the treatment of ambulatory patients with COVID-19
3. Regeneron 2069- A Phase 3, randomized, Double blind Placebo controlled Study assessing the efficacy and safety of Anti spike SARS- CoV2 Monoclonal antibodies in preventing SARS-CoV2 infection in household contacts of individuals with SARS- CoV2
4. Gates Foundation– A randomized, controlled, Phase 2b study to evaluate safety and efficacy of rivaroxaban (Xarelto®) for high risk people with mild COVID-19 (Bill & Melinda Gates Medical Research Institute)- Terminated
5. ACTIV-2- A study for Outpatients with COVID-19 (NIH-NIAID)
6. SAGE- Brexenalone in ARDS
7. ACTIV-3– Multicenter, Adaptive, Randomized, Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for Hospitalized Patients with COVID-19
8. Gilead– A Phase 1b/2a Study in Participants with Early Stage COVID-19 to Evaluate the Safety, Efficacy, and Pharmacokinetics of Remdesivir Administered by Inhalation
9. REGN 20145– phase 2 study to assess the virologic efficacy of REGN10933+ REGN10987 across different dose regimens in outpatients with SARS-COV-2 infection
10. Roche– A multicenter, phase III randomized, double-blind, placebo-controlled, outpatient study to evaluate the efficacy, safety, and antiviral activity of RO7496998 (AT-527) in patients with mild or moderate covid-19
11. FREEDOM COVID Anticoagulation Strategy Randomized Study
1. REGN 2040– An Adaptive Phase 2/3, Randomized, Double Blind, Placebo Controlled Study Assessing Efficacy and Safety of Sarilumab for Hospitalized Patients With COVID-19.
2. Genentech– – Phase II Randomized double-blind Placebo controlled multicenter study to evaluate the safety of MSTT1041A OR UTTR1147A in patients with severe COVID-19 pneumonia
3. Expanded Access to Convalescent Plasma for the Treatment of Patients with COVID-19
4. Expanded Access Treatment Protocol: Remdesevir (RDVGS-5734) For the Treatment of SARS-CoV2 (CoV) Infection
Recent Recognitions- PAGNY Research Awards
2 of our abstracts are selected as part of three top projects to deliver oral presentation on 2020 Research Day and vie for the top prize of $10K! (First prize is 10K, second prize is 5k and 3 rd prize is 2500k)
1)Predictors of Mortality in critically ill patients on mechanical ventilation for COVID-19 infections
2) Short term impact of COVID-19 pandemic in mental and social determinants of health in Ambulatory Care population in South Bronx, a pilot study
Additionally 2 more abstracts have been selected for the 250$ cash reward-
1) Clinical Features, Maternal and Fetal Outcomes in SARS-CoV2 PCR positive pregnant women admitted to a New York City hospital in the Bronx.
2) The Impact of the COVID-19 Pandemic on Burnout, PTSD, Coronavirus Anxiety, and Compassion Fatigue among Staffs at a Hospital in the Bronx
1) Increasing HIV PrEP screening and Prescription- A pilot Intervention Study
2)Citi Bike -Intervention to evaluate implementation of CITIbike program on glycemia control in prediabetes
3)Anemia- Prospective Longitudinal Comparative Outcome analysis of patients discharged with mild/moderate anemia and without anemia
4) cTn and ESRD- Prospective and Retrospective- Evaluation of Accuracy of Diagnosis of Myocardial Infarction, 30-Day Readmission and Six Month Mortality After Implementation of a Standardized Workflow for Hospitalized ESRD Patients with Elevated Troponin.
5) Patient Fall Experience- Effect of early mobilization in hospitalized patients
6) Implementation of Plant Based Diet program to improve control of Type 2 DM
7) CAP/HAP- Effect of Protocolized Pathway and Antibiotic Stewardship for Inpatient Community Acquired Pneumonia (CAP) and Hospital Acquired Pneumonia (HAP)
8) Case Series of Metformin Associated Lactic Acidosis
9)Optimum Pre-Discharge PRO BNP and Percentage Change from Admission to Discharge to Correlate with 30 Day Readmission in Patients after Decompensation of Heart Failure
10) Correlation of Platelet Count in Patients with Alcohol Withdrawal
11) Characteristics of Patients Presenting with Non-Cardiac Complaints and Elevated Cardiac Troponin I Levels (NCTI Study)
12) Comparing the Utility of CHADS2 vs. CHA2 DS2 – VASc Score in a Stroke Cohort with Atrial Fibrillation with Cerebrovascular Event
13) PCN Allergy- Retrospective review of “self-reported” PCN allergy
14) Advance Directives Knowledge Among Patients at Lincoln Medical Center.
15) Prevalence of Folic Acid and Vitamin B-12 Deficiency in the Inpatient and Outpatient Setting Among Community-Dwelling Adult Population in New York.
16) Optimization of BP control in Amb Care
17) Implementation of Outpatient Antimicrobial stewardship
18) COVID: Seroprevalence- Evaluation of Seroprevalence of Antibody to COVID-19 Virus among Healthcare Providers at Lincoln Hospital and Longitudinal follow-up
19) Understanding the Clinical Characteristics of Coronavirus Disease 2019 (COVID-19) Pandemic: Chart Review
a)COVID-Early/late Vent
b) COVID: Flex ICU vs Traditional ICU during surge
c) COVID: Renal Recovery following AKI and progression to AKD
d) Impact of Therapeutic Anticoagulation in hospitalized COVID-19 patients with COVID-19
e) Does HIV infection influence clinical course of Covid-19? Risk factors and outcomes in Covid-19 patients with and without HIV coinfection in New York City: an observational cohort study
f) Impact of Residential Neighborhood and Race/Ethnicity on Outcomes of Hospitalized
Patients with COVID-19 in the Bronx
g) COVID: BSI
h) Mental Health- prevalence of trauma related symptoms on personnel at H+H hospitals /Lincoln during covid-19 period
i) COVID: Radiology
j) COVID: Hydroxychloroquine
k) COVID: Famotidine
l) COVID: New Onset DM following COVID-19- A case series
m))COVID: Pregnancy
n) COVID: Steroids
o) COVID: Retrospective
p) COVID: Amb Care- Impact of COVID-19 pandemic on Physical, mental, Social determinants of Health In Amb Care
q) Comparison of short and long term outcomes after discharge between patients with COVID-19 requiring mech ventilation and those without COVID-19 requiring mechanical ventilation for sepsis
r) Knowledge Attitude and Perceptions of COVID-19 vaccination among Health care workers- Lincoln and System wide
s) Knowledge Attitude and Perceptions including Vaccine Hesitancy about COVID-19 vaccination in the South Bronx Community
